4-(3-(Trifluoromethyl)phenyl)tetrahydro-2h-pyran-4-amine hydrochloride CAS 1380300-52-6
| CAS No. | 1380300-52-6 |
| Molecular Formula | C12H14F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C12H14F3NOHCl, 4-(3-(Trifluoromethyl)phenyl)tetrahydro-2h-pyran-4-amine hydrochloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 281.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(3-(Trifluoromethyl)phenyl)tetrahydro-2h-pyran-4-amine hydrochloride (CAS 1380300-52-6) is a high-purity analytical reference standard with the molecular formula C12H14F3NOHCl and a molecular weight of 281.70 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14F3NO HCl |
| Molecular Weight | 281.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- Oxamyl (CAS 23135-22-0)
- 2-Amino-2-(3-(benzyloxy)phenyl)acetic acid (CAS 299169-37-2)
- H-Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly-OH (H-5445.0001) (CAS 81156-93-6)
- 3-(((Furan-2-ylmethyl)(methyl)amino)methyl)benzonitrile (CAS 1153512-67-4)
- Dimethyl (2S,6R)-piperidine-2,6-dicarboxylate hydrochloride (CAS 59234-48-9)
- 1-Bromo-4-fluoro-2-methoxy-5-nitrobenzene (CAS 935288-20-3)
- GSK 137647A (CAS 349085-82-1)
- 3,4-Dimethoxy-N-(o-tolyl)benzamide (CAS 5648-32-8)
- 3-(4-Bromo-3-fluorophenyl)propiolic acid (CAS 1339425-98-7)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
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