4,4-Difluoro-1-isobutylcyclohexane-1-carboxylic acid CAS 1380300-79-7
| CAS No. | 1380300-79-7 |
| Molecular Formula | C11H18F2O2 |
| Molecular Weight | 220.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4,4-Difluoro-1-isobutylcyclohexane-1-carboxylic acid (CAS 1380300-79-7), molecular formula C11H18F2O2 and molecular weight 220.26 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 4,4-Difluoro-1-isobutylcyclohexane-1-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H18F2O2 |
| Molecular Weight | 220.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
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Recommended Standards
- Benzyl trans-3-hydroxy-3-methylcyclobutane-1-carboxylate (CAS 1375746-91-0)
- Ethyl 4-butyrylbenzoate (CAS 1383800-57-4)
- 3-Formyl-2,4,6-trimethylbenzyl acetate (CAS 137380-48-4)
- 4-(Cyclohexyloxy)benzoic acid (CAS 139-61-7)
- 5,5-dimethyl-5H-thieno[3,2-b]pyran (CAS 129969-32-0)
- 5-(O-tolyl)-4-(p-tolyl)-4h-1,2,4-triazole-3-thiol (CAS 893725-02-5)
- n-Methylcyclopropanesulfonamide (CAS 180891-39-8)
- Prop-1-ene-1,3-diyldibenzene (CAS 5209-18-7)
- 2-(2-Aminoethyl)-6-phenyl-3(2H)-pyridazinone Hydrochloride (CAS 82362-87-6)
- Ethyl 6-oxo-6-(4-pentyloxyphenyl)hexanoate (CAS 898757-81-8)
- 3-Iodo-2,5-dimethylpyridine (CAS 1806451-35-3)
- (5-Fluoro-2-(methylthio)phenyl)boronic acid (CAS 1218790-65-8)
- 1-(5-(Tert-butyl)isoxazol-3-yl)-3-(3-chlorophenyl)urea (CAS 852670-31-6)
- Neuropeptide K, porcine (CAS 106441-70-7)
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