(4-(3-(Trifluoromethyl)benzyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride CAS 1380300-85-5
| CAS No. | 1380300-85-5 |
| Molecular Formula | C14H18F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-(3-(Trifluoromethyl)benzyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride (CAS 1380300-85-5), molecular formula C14H18F3NOHCl and molecular weight 309.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4-(3-(Trifluoromethyl)benzyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride (C14H18F3NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (4-(3-(Trifluoromethyl)benzyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18F3NO HCl |
| Molecular Weight | 309.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde (CAS 137017-45-9)
- 6-(Thiazol-2-yl)pyridazin-3(2H)-one (CAS 1103508-50-4)
- Behenin (CAS 6916-74-1)
- (4S)-Propyl 4-ethyl-3,4-dihydroxy-8-methoxy-3,4-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxylate (CAS 194999-55-8)
- 1-{[(Propan-2-yl)amino]methyl}naphthalen-2-ol (CAS 95768-31-3)
- Tert-butyl 4-(2-chlorophenyl)-4-cyanopiperidine-1-carboxylate (CAS 186347-31-9)
- 2,2'-Dimethylazoxybenzene (CAS 956-31-0)
- (2E)-2-Hydrazinylidene-1,2-diphenylethan-1-ol (CAS 109163-05-5)
- 4-(1-Imidazolyl)-1-butanamine (CAS 67319-76-0)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
Why CATO?
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