2-Ethyl-2,8-diazaspiro[4.5]decan-3-one CAS 1380386-77-5
| CAS No. | 1380386-77-5 |
| Molecular Formula | C10H18N2O |
| Molecular Weight | 182.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Ethyl-2,8-diazaspiro[4.5]decan-3-one (C10H18N2O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-Ethyl-2,8-diazaspiro[4.5]decan-3-one (CAS 1380386-77-5), molecular formula C10H18N2O and molecular weight 182.26 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H18N2O |
| Molecular Weight | 182.26 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 2-Methyl-2,9-diazaspiro[5.5]Undecan-1-one (CAS 1187228-01-8)
- 9-Methyl-2,9-diazaspiro[5.5]undecan-1-one (CAS 1228552-71-3)
- 1,4-diazaspiro[5.6]dodecan-5-one (CAS 1239746-72-5)
- 3,9-Diazaspiro[5.6]dodecan-10-one (CAS 1268334-89-9)
- 7,11-Diazaspiro[5.6]dodecan-12-one (CAS 1354349-47-5)
- 7,11-diazaspiro[5.6]dodecan-10-one (CAS 1494038-28-6)
- 1-(1,8-Diazaspiro[4.5]Decan-1-yl)ethan-1-one (CAS 1784089-80-0)
- 1-(2,8-Diazaspiro[4.5]decan-2-yl)ethan-1-one (CAS 870082-43-2)
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