2-[3-(tert-Butoxycarbonyl-amino-methyl)-5-chloro-1H-indol-2-yl]-4-methyl-pentanoic acid methyl ester CAS 1380571-60-7
| CAS No. | 1380571-60-7 |
| Molecular Formula | C21H29ClN2O4 |
| Molecular Weight | 408.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-[3-(tert-Butoxycarbonyl-amino-methyl)-5-chloro-1H-indol-2-yl]-4-methyl-pentanoic acid methyl ester (C21H29ClN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-[3-(tert-Butoxycarbonyl-amino-methyl)-5-chloro-1H-indol-2-yl]-4-methyl-pentanoic acid methyl ester (CAS 1380571-60-7), molecular formula C21H29ClN2O4 and molecular weight 408.92 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[3-(tert-Butoxycarbonyl-amino-methyl)-5-chloro-1H-indol-2-yl]-4-methyl-pentanoic acid methyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H29ClN2O4 |
| Molecular Weight | 408.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related tert Standards
- 5-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)ethyl)-4-oxo-3a,4,5,6,7,8-hexahydro-3H-pyrazolo[1,5-a][1,4]diazepine-2-carboxylic acid (CAS 163213-39-6)
- 2-((tert-Butoxycarbonyl)amino)-4-(2-((tert-butoxycarbonyl)amino)phenyl)-4-oxobutanoic acid (CAS 1219434-68-0)
- 2-(8-(Tert-butoxycarbonyl)-1-(cyclohexylmethyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-3-yl)acetic acid (CAS 180386-37-2)
- 2-((Tert-butoxycarbonyl)amino)-3-(3',4'-dichloro-[1,1'-biphenyl]-4-yl)propanoic acid (CAS 1259976-84-5)
- 3-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-3-[(bentyloxycarbonyl)amino]propanoic acid (CAS 372144-07-5)
- (1-(tert-Butoxycarbonyl)-5-(((tert-butyldimethylsilyl)oxy)methyl)-1H-indol-2-yl)boronic acid (CAS 335649-84-8)
- (1-(tert-butoxycarbonyl)-6-(((tert-butyldimethylsilyl)oxy)methyl)-1H-indol-2-yl)boronic acid (CAS 501364-51-8)
- 2-(4-((((Tert-butoxycarbonyl)-L-phenylalanyl)oxy)methyl)phenyl)acetic acid (CAS 67521-50-0)
Recommended Standards
- 2-(Difluoromethyl)-3,5-diiodopyridine-4-carboxaldehyde (CAS 1806898-49-6)
- (R)-2-Chloro-6-(2-hydroxy-3-((2-methyl-1-(naphthalen-2-yl)propan-2-yl)amino)propoxy)benzonitrile (CAS 284035-33-2)
- 2-(Difluoromethyl)-3,6-diiodopyridine-4-carboxaldehyde (CAS 1806032-85-8)
- 1-(4-Chlorophenyl)-3-{[(3-fluorophenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 439096-92-1)
- Bisphenol A propoxylate (CAS 37353-75-6)
- [(4-Chlorophenyl)sulfanyl]formonitrile (CAS 3226-37-7)
- 1-Methoxy-N-((3-methyl-1h-pyrazol-4-yl)methyl)propan-2-amine (CAS 1156721-45-7)
- AZD 4320 (CAS 1357576-48-7)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-(thieno[2,3-d]pyrimidin-4-yloxy)acetamide (CAS 756857-71-3)
- 8-Iodo-6-methylimidazo[1,2-a]pyridine (CAS 955942-40-2)
- 4-(2-Fluorophenyl)piperidine-2,6-dione (CAS 1268102-56-2)
- 4-Ethyl-5-morpholino-4H-1,2,4-triazole-3-thiol (CAS 847783-74-8)
- 2-(4-Benzyloxyphenyl)-4-hydroxypyridine (CAS 1261975-11-4)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com