4-(3,3-Difluoroazetidin-1-yl)piperidine hydrochloride CAS 1380680-50-1
| CAS No. | 1380680-50-1 |
| Molecular Formula | C8H14F2N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 212.67 g/mol gives 4-(3,3-Difluoroazetidin-1-yl)piperidine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(3,3-Difluoroazetidin-1-yl)piperidine hydrochloride (CAS 1380680-50-1), molecular formula C8H14F2N2HCl and molecular weight 212.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(3,3-Difluoroazetidin-1-yl)piperidine hydrochloride (C8H14F2N2HCl) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(3,3-Difluoroazetidin-1-yl)piperidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H14F2N2 HCl |
| Molecular Weight | 212.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Difluoroazetidin Standards
- 6-(3,3-Difluoroazetidin-1-yl)pyridin-3-amine (CAS 1045335-19-0)
- 4-(3,3-Difluoroazetidin-1-yl)piperidine (CAS 1093066-73-9)
- 4-(3,3-Difluoroazetidin-1-yl)aniline (CAS 1147706-70-4)
- 3,3-Difluoroazetidin-1-amine hydrochloride (CAS 1263145-19-2)
- 4-(3,3-Difluoroazetidin-1-yl)piperidine dHCl (CAS 1373503-66-2)
- (E)-4-(3,3-Difluoroazetidin-1-yl)but-2-enoic acid hydrochloride (CAS 1508257-75-7)
- 2-(3,3-difluoroazetidin-1-yl)ethan-1-ol (CAS 1638364-09-6)
- (3,3-Difluoroazetidin-2-yl)methanol (CAS 1638768-50-9)
Recommended Standards
- 3-(Furan-2-yl)-N-methylpropan-1-amine (CAS 17369-80-1)
- 10-(3-Nitrophenyl)-14-phenyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6-tetraen-12-one (CAS 330557-62-5)
- Dodecasodium phytate (CAS 17211-15-3)
- 2-Methyl-2-[(methylamino)methyl]propane-1,3-diol (CAS 82718-60-3)
- 4-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid (CAS 1368893-06-4)
- 2-Bromo-5-(1,1-dimethylheptyl)phenol (CAS 70120-14-8)
- 3-Cyclopropoxy-4-methoxy-5-(methylthio)pyridine (CAS 1243368-10-6)
- 4-(4-Chlorophenyl)-N-methylthiazol-2(3H)-imine (CAS 21344-78-5)
- N-(4-fluorophenyl)-N-methylmethanesulfonamide (CAS 36035-48-0)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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