4-Fluoro-2-(thiazol-5-ylmethyl)isoindoline-1,3-dione CAS 1381925-25-2
| CAS No. | 1381925-25-2 |
| Molecular Formula | C12H7FN2O2S |
| Molecular Weight | 262.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Fluoro-2-(thiazol-5-ylmethyl)isoindoline-1,3-dione.
CATO supplies 4-Fluoro-2-(thiazol-5-ylmethyl)isoindoline-1,3-dione (CAS 1381925-25-2), a certified reference material (molecular formula C12H7FN2O2S, MW 262.26 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-2-(thiazol-5-ylmethyl)isoindoline-1,3-dione (C12H7FN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Fluoro-2-(thiazol-5-ylmethyl)isoindoline-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7FN2O2S |
| Molecular Weight | 262.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Rutaretin (CAS 13895-92-6)
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- 1-(2-Hydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (CAS 2198-19-8)
- (R)-1-(2-Fluorophenyl)ethanamine hydrochloride (CAS 1168139-43-2)
- 2-ethyl-7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-amine (CAS 2759132-61-9)
- N-(furan-2-ylmethyl)-3-methyl-1-(p-tolyl)but-3-en-1-amine (CAS 436087-19-3)
- Methyl 5-chloro-1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 338977-75-6)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
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