1-ethyl-6,7-difluoro-2-methyl-1H-1,3-benzodiazole CAS 1381944-71-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1381944-71-3
Molecular FormulaC10H10F2N2
Molecular Weight196.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-ethyl-6,7-difluoro-2-methyl-1H-1,3-benzodiazole CAS 1381944-71-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-ethyl-6,7-difluoro-2-methyl-1H-1,3-benzodiazole.

1-ethyl-6,7-difluoro-2-methyl-1H-1,3-benzodiazole (CAS 1381944-71-3) is a high-purity analytical reference standard with the molecular formula C10H10F2N2 and a molecular weight of 196.20 g/mol.

The molecular framework of 1-ethyl-6,7-difluoro-2-methyl-1H-1,3-benzodiazole (C10H10F2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H10F2N2
Molecular Weight196.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms2

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