Febuxostat Impurity 75 CAS 138330-01-5
| CAS No. | 138330-01-5 |
| Molecular Formula | C10H9NOS |
| Molecular Weight | 191.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Febuxostat Impurity 75 (CAS 138330-01-5, C10H9NOS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H9NOS, Febuxostat Impurity 75 contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 191.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Febuxostat Impurity 75 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9NOS |
| Molecular Weight | 191.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Febuxostat Standards
- Febuxostat impurity 37 (CAS 1229019-33-3)
- Febuxostat Impurity 32 (CAS 1805770-41-5)
- Febuxostat impurity 36 (CAS 1805770-40-4)
- Febuxostat Impurity 34 (CAS 18962-07-7)
- Febuxostat Impurity 44 (CAS 79836-78-5)
- Febuxostat Impurity 19 (CAS CATO-C4X-116219)
- Febuxostat Impurity 50 (CAS 609-15-4)
- Febuxostat Impurity 39 (CAS 161718-85-0)
Recommended Standards
- 38942-51-7 4H-1,2,4-Triazole-3-thiol, 4-methyl-5-phenyl- G-32465 2,4-Dihydro-4-methyl-5-phenyl-3H-1,2,4-triazole-3-thione ENT 25,558-X Geigy G-32465 3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-methyl-5-phenyl- (CAS 38942-51-7)
- Tiopronin Impurity 5 (CAS CATO-C4X-15165)
- Spiro[benzo[b][1,4]thiazine-2,1'-cyclopropan]-3(4H)-one (CAS 681286-61-3)
- Piperacillin Impurity 26 (CAS 15537-71-0)
- Lomustine EP Impurity B (CAS 13908-11-7)
- Docetaxel Impurity 27 (CAS CATO-C4X-161927)
- Prucalopride Impurity 5 (CAS 1599434-55-5)
- N-isopropyl-4-methylthiazol-2-amine (CAS 89852-42-6)
- O-(Tert-butyldimethylsilyl) (CAS 165065-02-1)
- Ethyl 4-[(2,4-dimethylphenyl)sulfanyl]-8-(trifluoromethyl)quinoline-3-carboxylate (CAS 477847-17-9)
- 2-(4-Bromo-1-ethyl-1h-pyrazol-3-yl)acetonitrile (CAS 1310379-47-5)
- 2-(3-Aminophenyl)-n-cyclopropylacetamide (CAS 1018525-62-6)
- 5-Bromo-1-isobutyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1780474-56-7)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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