5,7-dichloro-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS 1384429-57-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1384429-57-5
Molecular FormulaC10H11Cl2N
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5,7-dichloro-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS 1384429-57-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 252.56 g/mol gives 5,7-dichloro-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5,7-dichloro-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1384429-57-5), molecular formula C10H11Cl2NHCl and molecular weight 252.56 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 5,7-dichloro-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 252.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5,7-dichloro-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H11Cl2N HCl
Molecular Weight252.56 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms1

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