(1R)-1-[2-(difluoromethoxy)-4-fluorophenyl]ethan-1-amine hydrochloride CAS 1384435-41-9
| CAS No. | 1384435-41-9 |
| Molecular Formula | C9H10F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(1R)-1-[2-(difluoromethoxy)-4-fluorophenyl]ethan-1-amine hydrochloride (CAS 1384435-41-9) is a high-purity analytical reference standard with the molecular formula C9H10F3NOHCl and a molecular weight of 241.64 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (1R)-1-[2-(difluoromethoxy)-4-fluorophenyl]ethan-1-amine hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10F3NO HCl |
| Molecular Weight | 241.64 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 2-(2-(Difluoromethoxy)phenyl)ethan-1-ol (CAS 1000533-82-3)
- 4-(Difluoromethoxy)-2-iodoaniline (CAS 1000801-26-2)
- 3-(4-(Difluoromethoxy)phenyl)propanoic acid (CAS 1000932-18-2)
- 4-(Difluoromethoxy)-2-fluoroaniline (CAS 1003865-65-3)
- (4-(Difluoromethoxy)-2-fluorophenyl)boronic acid (CAS 1004775-34-1)
- 4,6-Bis(difluoromethoxy)-2-(methylthio)pyrimidine (CAS 100478-25-9)
- 1-(3-(Difluoromethoxy)phenyl)-3-(1,5-dimethyl-1H-pyrazol-4-yl)prop-2-en-1-one (CAS 1005647-45-9)
- Methyl 6-(4-(difluoromethoxy)phenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1011396-51-2)
Recommended Standards
- 4-(3,4,5-Trimethyl-1H-pyrazol-1-yl)benzoic acid (CAS 1266374-21-3)
- 1H-Benzo[d][1,2,3]triazol-5-amine hemisulfate (CAS 93805-10-8)
- 2-Amino-4-(2,4-dichlorophenyl)-6-(4-methoxyphenyl)nicotinonitrile (CAS 338793-82-1)
- 4-(3-Bromophenyl)tetrahydro-2H-pyran-4-amine (CAS 1094477-13-0)
- Ribavirin EP Impurity F (CAS 58151-87-4)
- 2-((2-Cyanophenyl)sulfonyl)-N-isopropylbenzamide (CAS 477885-85-1)
- (E)-3-(4,5-difluoro-2-methoxyphenyl)acrylic acid (CAS 886499-69-0)
- 3-(1h-1,2,4-Triazol-1-yl)propan-1-amine dihydrochloride (CAS 637015-66-8)
- 2-(4-Bromobenzyl)-1H-pyrrole (CAS 1293391-65-7)
- 30003-72-6 insulin chain b oxidized (CAS 30003-72-6)
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