(3,4-Dimethoxy-2-(trifluoromethyl)phenyl)methanol CAS 138490-98-9
| CAS No. | 138490-98-9 |
| Molecular Formula | C10H11F3O3 |
| Molecular Weight | 236.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(3,4-Dimethoxy-2-(trifluoromethyl)phenyl)methanol (CAS 138490-98-9) is a high-purity analytical reference standard with the molecular formula C10H11F3O3 and a molecular weight of 236.19 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (3,4-Dimethoxy-2-(trifluoromethyl)phenyl)methanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H11F3O3 |
| Molecular Weight | 236.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
Related Dimethoxy Standards
- 3,5-Dimethoxy-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1247789-27-0)
- 6,7-Dimethoxy-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid (CAS 148050-74-2)
- 2-(5,6-Dimethoxy-1H-indazol-3-yl)acetic acid (CAS 199533-43-2)
- 6,7-Dimethoxy-3-methylbenzofuran-2-carboxylic acid (CAS 63445-53-4)
- 6,7-Dimethoxy-3-methylquinazoline-2,4(1H,3H)-dione (CAS 20197-88-0)
- 6,7-Dimethoxy-8-nitro-3,4-dihydroisoquinoline (CAS 917892-74-1)
- Methyl 5,6-dimethoxy-1H-indazole-3-carboxylate (CAS 885279-34-5)
- 2,6-Dimethoxy-4-(prop-1-en-1-yl)phenyl acetate (CAS 29540-10-1)
Recommended Standards
- 2-((Dimethylamino)methylene)-1-(2,2,2-trifluoroacetyl)pyrrolidin-3-one (CAS 1383734-88-0)
- tert-Butyl 4-(trifluoromethyl)-1H-imidazole-1-carboxylate (CAS 1393532-66-5)
- 2-Methyl-6-(trifluoromethyl)quinoline-4-carbonitrile (CAS 1367803-93-7)
- 2-(1-Isopropyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)acetic acid (CAS 1402445-82-2)
- 5-Bromo-4-methyl-1-(4-((7-methyl-2-propyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-1H-pyrrole-2-carbonitrile (CAS 142016-06-6)
- 17a(H)-22,29,30-Trisnorhopane (CAS 53584-59-1)
- (E)-2-(2-Fluorophenyl)-3-[3-(2-pyrimidinyloxy)phenyl]-2-propenenitrile (CAS 861210-17-5)
- 1-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)ethan-1-one (CAS 1254044-15-9)
- 1-(4-Ethyl-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)pyrrolidine-3-carboxylic acid (CAS 1707399-72-1)
- tert-Butyl (3'-hydroxy-5'-methyl-[1,1'-biphenyl]-4-yl)carbamate (CAS 1261890-14-5)
- 1-Fluoro-4-(propane-2-sulfonyl)benzene (CAS 70399-09-6)
- 1-Tert-butyl-3-methyl-1h-pyrazol-5-ol (CAS 1020661-22-6)
- Ethyl 2,2-Difluoropropionate (CAS 28781-85-3)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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