Silodosin Impurity 18 CAS 1384966-05-5
| CAS No. | 1384966-05-5 |
| Molecular Formula | C25H28F3N3O5 |
| Molecular Weight | 507.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Silodosin Impurity 18 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Silodosin Impurity 18 (CAS 1384966-05-5, C25H28F3N3O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Silodosin Impurity 18 (C25H28F3N3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 507.50 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Silodosin Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H28F3N3O5 |
| Molecular Weight | 507.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Silodosin Standards
Recommended Standards
- 4'-Bromo-2,7-di-tert-butyl-9,9'-spirobi[fluorene] (CAS 1365480-13-2)
- 2’-Bromo-2,7-di-tert-butyl-9,9’-spirobi[fluorene] (CAS 393841-81-1)
- 7-Cyanomethotrexate Dimethyl Ester (CAS 112163-39-0)
- N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-((4-methoxybenzyl)oxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)benzamide (CAS 80015-56-1)
- Atrasentan Impurity 41 (CAS 178738-93-7)
- Limaprost Impurity 8 (CAS CATO-C4X-21458)
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- 2-Aminodecahydronaphthalene-2-carboxylic acid (CAS 18672-74-7)
- 2-Bromo-n-(3-tert-butyl-1,2-oxazol-5-yl)acetamide (CAS 92944-37-1)
- 1-(1-Tosyl-1H-pyrrol-3-yl)ethanone (CAS 106058-85-9)
- 2-Ethyl-4-(2-methylpropylidene)oxazol-5(4H)-one (CAS 538339-48-9)
- 4-Nitro-7-phenoxybenzo[c][1,2,5]oxadiazole (CAS 16597-10-7)
- (4-Chloromethyl-cyclohexyl)-dimethyl-amine (CAS 1353989-47-5)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
Why CATO?
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