1-(2-Aminoethyl)-1H-indole-5-carbonitrile CAS 1385027-30-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Aminoethyl)-1H-indole-5-carbonitrile.

1-(2-Aminoethyl)-1H-indole-5-carbonitrile (CAS 1385027-30-4), molecular formula C11H11N3 and molecular weight 185.23 g/mol, is a CATO reference standard with documented purity and traceability.

1-(2-Aminoethyl)-1H-indole-5-carbonitrile (C11H11N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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