Olanzapine Impurity 5 CAS 138564-60-0
| CAS No. | 138564-60-0 |
| Molecular Formula | C12H11N3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Olanzapine Impurity 5 (C12H11N3SHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 265.76 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Olanzapine Impurity 5 (CAS 138564-60-0) is a certified pharmaceutical impurity reference standard with the molecular formula C12H11N3SHCl and a molecular weight of 265.76 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11N3S HCl |
| Molecular Weight | 265.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Olanzapine Standards
- Olanzapine Impurity 20 (CAS 1017241-34-7)
- Olanzapine Impurity 11 (CAS 1017241-36-9)
- Olanzapine Impurity 19 (CAS 1070876-09-3)
- Olanzapine-d8 (CAS 1093380-13-2)
- Olanzapine Impurity 39 (CAS 1319722-10-5)
- Olanzapine Impurity 9 (CAS 1320360-86-8)
- Olanzapine Impurity 8 (CAS 1320360-87-9)
- Olanzapine (CAS 132539-06-1)
Recommended Standards
- Gabapentin Impurity 16 (CAS 1281568-83-9)
- Sertraline EP Impurity F (CAS 155748-61-1)
- Tinidazole Impurity N1 (CAS 52455-84-2)
- PF-04447943 (CAS 1082744-20-4)
- Tert-butyln-(2-methyl-5-oxo-pyrrolidin-3-yl)carbamate (CAS 1824602-08-5)
- (E)-2-(Trityloxyimino)-2-[2-(tritylamino)thiazol-4-yl]acetic Acid (CAS 69689-81-2)
- 1,12-Bis[4-methyl-5-(2-hydroxyethyl)thiazol-3-ium-3-yl]dodecanedibromide (CAS 321915-72-4)
- 4-Methoxy-1-benzofuran-7-carbaldehyde (CAS 59254-24-9)
- Palmityl Myristate (CAS 2599-01-1)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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