6-Bromo-2,4-dichloroquinoline-3-carbonitrile CAS 138580-81-1

Purity 97%+In StockPharmaceutical Standards
CAS No.138580-81-1
Molecular FormulaC10H3BrCl2N2
Molecular Weight301.95 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-2,4-dichloroquinoline-3-carbonitrile CAS 138580-81-1 chemical structure

Description

The occurrence of 6-Bromo-2,4-dichloroquinoline-3-carbonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Bromo-2,4-dichloroquinoline-3-carbonitrile (CAS 138580-81-1), molecular formula C10H3BrCl2N2 and molecular weight 301.95 g/mol, is a CATO reference standard with documented purity and traceability.

6-Bromo-2,4-dichloroquinoline-3-carbonitrile (C10H3BrCl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Bromo-2,4-dichloroquinoline-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H3BrCl2N2
Molecular Weight301.95 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1996
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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