3-((4-Fluorophenyl)ethynyl)aniline CAS 138781-97-2
| CAS No. | 138781-97-2 |
| Molecular Formula | C14H10FN |
| Molecular Weight | 211.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-((4-Fluorophenyl)ethynyl)aniline.
3-((4-Fluorophenyl)ethynyl)aniline (CAS 138781-97-2), molecular formula C14H10FN and molecular weight 211.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((4-Fluorophenyl)ethynyl)aniline (C14H10FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((4-Fluorophenyl)ethynyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10FN |
| Molecular Weight | 211.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 3-(4-Fluorophenyl)-1H-indole (CAS 101125-32-0)
- 2-((4-Fluorophenyl)ethynyl)aniline (CAS 1173153-20-2)
- Methyl 2-(4-fluorophenyl)-2-(methylamino)propanoate (CAS 1178781-92-4)
- 7-(3-Fluorophenyl)-1h-indole (CAS 1214329-23-3)
- Ethyl 2-(4-fluorophenyl)-2-(methylamino)acetate (CAS 1218313-52-0)
- 2-(3-Fluorophenyl)-1H-indole (CAS 124643-63-6)
- N-(1-(4-fluorophenyl)ethyl)-N-methylglycine (CAS 1353976-40-5)
- 5-(4-Fluorophenyl)-1H-indole (CAS 144104-44-9)
Recommended Standards
- 2-Fluoro-4-(3-methylphenyl)benzonitrile (CAS 1381944-81-5)
- tert-Butyl 4-Amino-2-fluorobenzoate (CAS 140373-77-9)
- 3-(2-Fluoro-5-methylphenyl)benzonitrile (CAS 1365272-20-3)
- 2-(3-Fluoro-4-methylphenyl)benzonitrile (CAS 136042-62-1)
- N-((2-Chloro-6-methoxyquinolin-3-yl)methyl)-N-(2-methoxyethyl)-4-methylbenzamide (CAS 606103-09-7)
- endo-tert-Butyl 3-azabicyclo[3.1.1]heptan-6-ylcarbamate (CAS 1614256-81-3)
- 2-Amino-4-(3,5-dimethoxyphenyl)-6-(hydroxymethyl)-8-oxo-4H,8H-pyrano[3,2-b]pyran-3-carbonitrile (CAS 876709-87-4)
- 4,6-Dichloropyrimidine-5-sulfonyl chloride (CAS 1216003-03-0)
- 1,2-Bis(1-(7-chloroquinazolin-4-yl)piperidin-4-yl)ethane (CAS 52791-50-1)
- 1-(5-Bromopyridin-2-yl)-2-chloroethan-1-one (CAS 1260759-84-9)
- n-(4-Methylpentan-2-yl)-2-(methylthio)aniline (CAS 1154296-52-2)
- 3,3-dimethylpiperidine-2-carbonitrile (CAS 344410-47-5)
- 2-Oxa-7-azaspiro[4.4]nonane hydrochloride (CAS 1419590-58-1)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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