(3S)-3-(trifluoromethyl)morpholine CAS 1389360-68-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1389360-68-2
Molecular FormulaC5H8F3NO
Molecular Weight155.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3S)-3-(trifluoromethyl)morpholine CAS 1389360-68-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 155.12 g/mol gives (3S)-3-(trifluoromethyl)morpholine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(3S)-3-(trifluoromethyl)morpholine (CAS 1389360-68-2), molecular formula C5H8F3NO and molecular weight 155.12 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (3S)-3-(trifluoromethyl)morpholine (C5H8F3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (3S)-3-(trifluoromethyl)morpholine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H8F3NO
Molecular Weight155.12 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms1

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