2-(4-(3-Hydroxypiperidin-1-yl)piperazin-2-yl)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 5,5-dioxide CAS 139086-70-7
| CAS No. | 139086-70-7 |
| Molecular Formula | C16H25N5O4S |
| Molecular Weight | 383.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-(3-Hydroxypiperidin-1-yl)piperazin-2-yl)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 5,5-dioxide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-(3-Hydroxypiperidin-1-yl)piperazin-2-yl)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 5,5-dioxide (CAS 139086-70-7), molecular formula C16H25N5O4S and molecular weight 383.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-(3-Hydroxypiperidin-1-yl)piperazin-2-yl)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 5,5-dioxide (C16H25N5O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-(3-Hydroxypiperidin-1-yl)piperazin-2-yl)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 5,5-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H25N5O4S |
| Molecular Weight | 383.47 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
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Recommended Standards
- N-(4-Methylthiazol-2-yl)-5-(N-(thiophen-2-ylmethyl)sulfamoyl)furan-2-carboxamide (CAS 1172807-76-9)
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- 2-(Benzylthio)-1-(4-(3-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)piperazin-1-yl)ethan-1-one (CAS 1058232-38-4)
- (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-((6-mercaptohexyl)oxy)tetrahydrofuran-3-ol (CAS 162821-80-9)
- N-methylindan-1-amine (CAS 2084-72-2)
- 2-Bromo-4-(((cyclopropylmethyl)amino)methyl)phenol (CAS 1247864-01-2)
- 3-(4-Nitrophenyl)-5-(1-phenylpropyl)-1,2,4-oxadiazole (CAS 434312-23-9)
- Potassium trifluoro(2-methylallyl)borate (CAS 1499174-62-7)
- N-benzyl-2-(N-phenylphenylsulfonamido)acetamide (CAS 339103-45-6)
- 3-(Chloromethyl)-5-nitrobenzyl Alcohol (CAS 2069250-63-9)
- 8-Methylquinolin-6-amine (CAS 77094-04-3)
- (2-Fluoro-6-methoxyphenyl)methanamine hydrochloride (CAS 1214366-31-0)
- 2-(5,5-Dimethyl-2-oxooxolan-3-yl)acetic acid (CAS 412298-86-3)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
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