4-Acetyl-6-iodopyridine-2-sulfonyl chloride CAS 1393533-67-9
| CAS No. | 1393533-67-9 |
| Molecular Formula | C7H5ClINO3S |
| Molecular Weight | 345.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Acetyl-6-iodopyridine-2-sulfonyl chloride (C7H5ClINO3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Acetyl-6-iodopyridine-2-sulfonyl chloride (CAS 1393533-67-9), molecular formula C7H5ClINO3S and molecular weight 345.54 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Acetyl-6-iodopyridine-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClINO3S |
| Molecular Weight | 345.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Acetyl Standards
- 4-iodopyridine-3-carboxylic acid (CAS 15366-63-9)
- 4-Iodopyridine-2,6-dicarboxylic acid (CAS 506423-80-9)
- 1,1'-(6-Iodopyridine-2,4-diyl)bis(ethan-1-one) (CAS 1393576-50-5)
- methyl 3-iodopyridine-4-carboxylate (CAS 188677-49-8)
- (4-Iodopyridine-2,6-diyl)dimethanol (CAS 120491-91-0)
- Methyl 5-iodopyridine-3-carboxylate (CAS 1033955-80-4)
- Methyl 4-Iodopyridine-2-carboxylate (CAS 380381-28-2)
- 4-Iodopyridine-2,6-dicarbaldehyde (CAS 506423-88-7)
Recommended Standards
- 4-(5-Bromo-6-chloro-4-(trifluoromethyl)pyridin-2-yl)morpholine (CAS 1053659-46-3)
- 1-(2-Bromo-4-(trifluoromethyl)phenyl)-3-(2-chloroethyl)urea (CAS 2407339-55-1)
- Dansylcadaverine (CAS 10121-91-2)
- 1,1-Dibutyl-2-[[(2,6-dimethylphenyl)amino]carbonyl]piperidinium (CAS 852804-30-9)
- N-(Allyloxycarbonyloxy)succinimide (CAS 135544-68-2)
- 3,5-Dibromo-1-{[4-chloro-3-(trifluoromethyl)phenyl]methyl}-1h-1,2,4-triazole (CAS 1240568-47-1)
- Ethyl 6-chloro-4-(trifluoromethyl)nicotinate (CAS 1260778-46-8)
- Methyl 6-(1-cyanocyclopropyl)picolinate (CAS 1956371-39-3)
- 4-(1,3-Dioxolan-2-yl)pyridine (CAS 61379-59-7)
- 2-Chloro-4-(4-fluorophenyl)nicotinonitrile (CAS 886362-05-6)
- 2,4,6-Tribromobenzoic acid (CAS 633-12-5)
- Methyl 5-oxo-4,5-dihydroisoxazole-3-carboxylate (CAS 882530-43-0)
- 9-Benzhydryl-10-methyl-9,10-dihydroacridine (CAS 138616-16-7)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
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