6-Fluoro-4-iodopyridine-2-sulfonyl chloride CAS 1393538-76-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1393538-76-5
Molecular FormulaC5H2ClFINO2S
Molecular Weight321.50 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Fluoro-4-iodopyridine-2-sulfonyl chloride CAS 1393538-76-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 321.50 g/mol gives 6-Fluoro-4-iodopyridine-2-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

6-Fluoro-4-iodopyridine-2-sulfonyl chloride (CAS 1393538-76-5), molecular formula C5H2ClFINO2S and molecular weight 321.50 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-Fluoro-4-iodopyridine-2-sulfonyl chloride (C5H2ClFINO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Fluoro-4-iodopyridine-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H2ClFINO2S
Molecular Weight321.50 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1991
Halogen ContentF/Cl/I-containing
Nitrogen Atoms1
Sulfur Atoms1

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