1-(4-(Chloromethyl)-6-(trifluoromethyl)pyridin-2-yl)ethan-1-one CAS 1393541-07-5
| CAS No. | 1393541-07-5 |
| Molecular Formula | C9H7ClF3NO |
| Molecular Weight | 237.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 237.61 g/mol gives 1-(4-(Chloromethyl)-6-(trifluoromethyl)pyridin-2-yl)ethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(4-(Chloromethyl)-6-(trifluoromethyl)pyridin-2-yl)ethan-1-one (CAS 1393541-07-5), a certified reference material (molecular formula C9H7ClF3NO, MW 237.61 g/mol) for analytical method development and quality control.
The molecular framework of 1-(4-(Chloromethyl)-6-(trifluoromethyl)pyridin-2-yl)ethan-1-one (C9H7ClF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF3NO |
| Molecular Weight | 237.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 1-(2-(Chloromethyl)-6-(trifluoromethyl)pyridin-4-yl)ethan-1-one (CAS 1393565-88-2)
- 1-(6-(Chloromethyl)-4-(trifluoromethyl)pyridin-2-yl)ethan-1-one (CAS 1393582-45-0)
- 2-(Chloromethyl)-4-(difluoromethyl)-3,6-dimethoxypyridine (CAS 1805325-11-4)
- 2-(Chloromethyl)-5-(difluoromethyl)-3,6-dimethoxypyridine (CAS 1806821-33-9)
- 4-(Chloromethyl)-5-(difluoromethyl)-3-nitropyridin-2-amine (CAS 1804685-52-6)
- 6-(Chloromethyl)-3-(difluoromethyl)-4-nitropyridin-2-amine (CAS 1804685-61-7)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-hydroxypyridine-5-carboxylic acid (CAS 1805092-05-0)
- 6-(Chloromethyl)-5-(difluoromethyl)-3-nitropyridin-2-amine (CAS 1805353-90-5)
Recommended Standards
- 4-Cyano-2,6-difluorobenzene-1-sulfonyl chloride (CAS 1384429-18-8)
- 6-Chloro-5-(trifluoromethyl)-2,3-dihydrobenzofuran-3-amine (CAS 1273598-63-2)
- 1-(4-Amino-5-chloro-2-(trifluoromethyl)phenyl)ethan-1-one (CAS 1260816-02-1)
- 1-(2-Amino-4-chloro-5-(trifluoromethyl)phenyl)ethanone (CAS 1698027-72-3)
- 8-Benzyl-4-(naphthalene-1-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-55-5)
- 5-Bromo-4-methoxypyrrolo[2,1-f][1,2,4]triazine (CAS 2144752-77-0)
- 2-Amino-6-hydroxy-N-methylbenzamide (CAS 1243360-93-1)
- 4-(1-Chloroisoquinolin-3-yl)morpholine (CAS 1050885-07-8)
- 3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (CAS 1648707-58-7)
- 4-Fluorobenzothioamide (CAS 22179-72-2)
- Benzo[d]thiazol-2-yl(3-((4-fluorophenyl)sulfonyl)azetidin-1-yl)methanone (CAS 1797688-88-0)
- 6-Chloro-N-cyclopropyl-1-(3-methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1206969-84-7)
- 5-Chloro-6-hydroxy-2,3-dihydro-1H-inden-1-one (CAS 1228678-18-9)
- Tetrapeptide-3 (CAS 827306-97-8)
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