2-Acetyl-5-hydroxyisonicotinaldehyde CAS 1393554-53-4
| CAS No. | 1393554-53-4 |
| Molecular Formula | C8H7NO3 |
| Molecular Weight | 165.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 165.15 g/mol gives 2-Acetyl-5-hydroxyisonicotinaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Acetyl-5-hydroxyisonicotinaldehyde (CAS 1393554-53-4), molecular formula C8H7NO3 and molecular weight 165.15 g/mol, is a CATO reference standard with documented purity and traceability.
2-Acetyl-5-hydroxyisonicotinaldehyde (C8H7NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Acetyl-5-hydroxyisonicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7NO3 |
| Molecular Weight | 165.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Acetyl Standards
Recommended Standards
- 6-Acetyl-4-hydroxynicotinaldehyde (CAS 1393539-74-6)
- 6-Acetyl-2-hydroxynicotinaldehyde (CAS 1393559-58-4)
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- 6-Acetyl-3-hydroxypicolinaldehyde (CAS 1393562-22-5)
- Sodium (R)-1-methoxypropane-2-sulfinate (CAS 1638587-20-8)
- 1-(4-Aminobenzyl)azetidin-3-ol (CAS 1044926-69-3)
- methyl 2-amino-2-(3-piperidyl)acetate (CAS 1261236-23-0)
- N1-(2-(Azepan-1-yl)-2-(thiophen-3-yl)ethyl)-N2-(2-methoxyethyl)oxalamide (CAS 946356-12-3)
- N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]benzenecarbohydrazide (CAS 685109-12-0)
- 2-Chloro-n-[2-methyl-5-(5-methyl-1h-1,2,4-triazol-3-yl)phenyl]acetamide (CAS 1394041-82-7)
- Suvorexant Impurity 37 (CAS CATO-C4X-181237)
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- 4-CHloro-2-fluoro-3-nitro-phenylamine (CAS 2090607-05-7)
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