2,4-Dichloro-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one CAS 1393572-20-7
| CAS No. | 1393572-20-7 |
| Molecular Formula | C7H5Cl2N3O |
| Molecular Weight | 218.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Dichloro-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one (CAS 1393572-20-7) is a high-purity analytical reference standard with the molecular formula C7H5Cl2N3O and a molecular weight of 218.04 g/mol.
The molecular framework of 2,4-Dichloro-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one (C7H5Cl2N3O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5Cl2N3O |
| Molecular Weight | 218.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 3,5-Difluoro-4-(trifluoromethoxy)benzoic acid (CAS 1360438-69-2)
- Rylugolimide Acetylates (CAS CATO-C4X-2429152)
- N-(2-Methylbenzyl)-4-(2-phenoxyethoxy)aniline (CAS 1040690-82-1)
- 9-(5-(3-(9H-Carbazol-9-yl)phenyl)pyridin-3-yl)-9H-carbazole (CAS 1583238-16-7)
- 4-((4-Hydroxycyclohexyl)amino)-3-methylbenzonitrile (CAS 1178262-47-9)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
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