1-(4-(Chloromethyl)-3-hydroxypyridin-2-yl)ethan-1-one CAS 1393575-18-2
| CAS No. | 1393575-18-2 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-(Chloromethyl)-3-hydroxypyridin-2-yl)ethan-1-one (CAS 1393575-18-2) is a high-purity analytical reference standard with the molecular formula C8H8ClNO2 and a molecular weight of 185.61 g/mol.
Structurally, 1-(4-(Chloromethyl)-3-hydroxypyridin-2-yl)ethan-1-one (C8H8ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 185.61 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1-(4-(Chloromethyl)-3-hydroxypyridin-2-yl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- Methyl 3-(Chloromethyl)pyridine-2-carboxylate (CAS 1196146-77-6)
- Methyl 4-(chloromethyl)pyridine-2-carboxylate (CAS 1206973-14-9)
- Methyl 2-(chloromethyl)pyridine-4-carboxylate (CAS 125104-36-1)
- Methyl 3-(chloromethyl)isonicotinate (CAS 1256804-52-0)
- 1-(2-(Chloromethyl)-4-hydroxypyridin-3-yl)ethan-1-one (CAS 1393551-84-2)
- 1-(5-(Chloromethyl)-2-hydroxypyridin-3-yl)ethan-1-one (CAS 1393558-84-3)
- 1-(3-(Chloromethyl)-5-hydroxypyridin-4-yl)ethan-1-one (CAS 1393574-88-3)
- Methyl 2-(chloromethyl)nicotinate (CAS 177785-14-7)
Recommended Standards
- 1-Chloro-3-(2-nitroethyl)benzene (CAS 140378-05-8)
- 4-Chloro-6-(dimethylamino)pyrimidine-5-carbaldehyde (CAS 14160-95-3)
- 8-Chloro-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one (CAS 1420367-14-1)
- 4-chloro-N-(hydroxymethyl)benzamide (CAS 13855-74-8)
- (1,3-Dicyclohexylimidazol-2-ylidene)copper(I) tert-butoxide (CAS 910806-89-2)
- 3-(2,4-Dioxothiazolidin-3-yl)propanoic acid (CAS 49629-36-9)
- 3-Acetyl-4-(4-hydroxy-3-methoxyphenyl)furan-2(5H)-one (CAS 73839-65-3)
- (2Z)-2-{[(2,4-difluorophenyl)amino](hydroxy)methylidene}-3-oxo-4-phenoxybutanenitrile (CAS 866151-81-7)
- (3R)-3-Propylpyrrolidine 74650-62-7 (CAS 74650-62-7)
- Vonoprazan Fumarate Impurity 49 (CAS 2416241-97-7(free base))
- (3-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)phenyl)boronic acid (CAS 90393-86-5)
- Isoamyl Benzoate (CAS 94-46-2)
- 2H-Indazole-2-acetic acid (CAS 58037-05-1)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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