2-Amino-3,3,3-trifluoro-2-(3-methoxyphenyl)propanoic acid CAS 1393585-33-5
| CAS No. | 1393585-33-5 |
| Molecular Formula | C10H10F3NO3 |
| Molecular Weight | 249.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Amino-3,3,3-trifluoro-2-(3-methoxyphenyl)propanoic acid (CAS 1393585-33-5) is a high-purity analytical reference standard with the molecular formula C10H10F3NO3 and a molecular weight of 249.19 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Amino-3,3,3-trifluoro-2-(3-methoxyphenyl)propanoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-Amino-3,3,3-trifluoro-2-(3-methoxyphenyl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10F3NO3 |
| Molecular Weight | 249.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- Methyl 4-amino-3-(2,2,2-trifluoroethoxy)benzoate (CAS 1096863-64-7)
- Methyl 3-amino-4-(2,2,2-trifluoroethoxy)benzoate (CAS 1096863-89-6)
- (S)-2-amino-3-(2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1103894-71-8)
- 2-Amino-3-(2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1218228-20-6)
- Methyl 2-amino-2-(2-(trifluoromethoxy)phenyl)acetate (CAS 1218713-63-3)
- (R)-3-Amino-3-(3-(trifluoromethoxy)phenyl)propanoic acid (CAS 1228558-79-9)
- (S)-3-Amino-3-(4-(trifluoromethoxy)phenyl)propanoic acid (CAS 1228560-97-1)
- (S)-3-Amino-3-(2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1228561-33-8)
Recommended Standards
- (2R,3R)-3-amino-2-hydroxy-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 1391423-37-2)
- 2-Amino-3,3,3-trifluoro-2-(2-methoxyphenyl)propanoic acid (CAS 1406834-27-2)
- 4-(2-Hydroxypropan-2-yl)-6-(trifluoromethyl)picolinic acid (CAS 1379375-74-2)
- (1R,4R)-5-(1-(trifluoromethyl)cyclopropane-1-carbonyl)-2-oxa-5-azabicyclo[2.2.1]Heptan-3-one (CAS 1434816-48-4)
- Pomalidomide-CO-PEG1-propargyl (CAS 2236109-19-4)
- (4-(Pentylthio)phenyl)methanol (CAS 1443330-59-3)
- 2802-68-8 Hydrogen trifluoromethoxyborate(1-), compound with methanol (1:1) Borate(1-), trifluoromethoxy-, (T-4)-, hydrogen, compd. with methanol (1:1:1) Borate(1-), trifluoromethoxy-, (T-4)-, hydrogen, compd. with methanol (1:1) Boron trifluoride, methanol complex EINECS 220-543-9 Boron trifluoride methanol complex (CAS 2802-68-8)
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