8-Bromo-5-nitroquinoline CAS 139366-35-1
| CAS No. | 139366-35-1 |
| Molecular Formula | C9H5BrN2O2 |
| Molecular Weight | 253.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-Bromo-5-nitroquinoline (CAS 139366-35-1) is a high-purity analytical reference standard with the molecular formula C9H5BrN2O2 and a molecular weight of 253.05 g/mol.
8-Bromo-5-nitroquinoline (C9H5BrN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 8-Bromo-5-nitroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrN2O2 |
| Molecular Weight | 253.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 6-Bromo-1,8-naphthyridine-3-carboxylic acid (CAS 1105191-97-6)
- 2-Bromo-5-nitroquinoline (CAS 116632-28-1)
- 3-Bromo-5-nitroquinoline (CAS 116632-33-8)
- 8-Bromo-6-nitroquinoline (CAS 120287-30-1)
- 2-Bromo-3-hydroxynaphthalene-1,4-dione (CAS 1203-39-0)
- 5-Bromo-1-nitroisoquinoline (CAS 1217440-57-7)
- 6-Bromo-4-oxo-3,4-dihydroquinazoline-2-carbaldehyde (CAS 1260898-14-3)
- 7-Bromo-5-nitroisoquinoline (CAS 1368385-65-2)
Recommended Standards
- 4-Bromo-8-nitroquinoline (CAS 1379345-02-4)
- 6-amino-7-bromo-5,8-dihydroquinoline-5,8-dione (CAS 14173-81-0)
- 8-Bromoquinoxaline-6-carboxylic acid (CAS 1378260-89-9)
- 6-Bromo-1,8-naphthyridine-2-carboxylic acid (CAS 1424939-70-7)
- 1,4-Dibutoxy-2,5-diiodobenzene (CAS 145483-70-1)
- 64671-30-3 (2-Fluorophenyl)(1-methylpiperidin-4-yl)methanone--hydrogen chloride (1/1) DTXSID10525113 (CAS 64671-30-3)
- 3-(Bromomethyl)-3-ethylhexane (CAS 1465073-72-6)
- 2-(Aminomethyl)-6-(trifluoromethyl)pyridin-4-ol (CAS 1393555-29-7)
- (3-Bromo-2-chloro-5-fluorophenyl)methanol (CAS 2090980-95-1)
- 2-Difluoromethyl-6-(trifluoromethyl)benzonitrile (CAS 1804515-80-7)
- 1-Cyclopentylpiperazine dihydrochloride (CAS 131269-35-7)
- Ethyl 2-(3,4-dichlorophenyl)-4-methylthiazole-5-carboxylate (CAS 317319-18-9)
- 2-((5-(3,4-Dimethylphenyl)thieno[2,3-d]pyrimidin-4-yl)amino)-2-phenylacetamide (CAS 1280785-43-4)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
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