3-[(tert-Butyldimethylsilyl)oxy]-4-methoxyphenol CAS 1394935-22-8
| CAS No. | 1394935-22-8 |
| Molecular Formula | C13H22O3Si |
| Molecular Weight | 254.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-[(tert-Butyldimethylsilyl)oxy]-4-methoxyphenol (CAS 1394935-22-8) is a high-purity analytical reference standard with the molecular formula C13H22O3Si and a molecular weight of 254.40 g/mol.
3-[(tert-Butyldimethylsilyl)oxy]-4-methoxyphenol (C13H22O3Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H22O3Si |
| Molecular Weight | 254.40 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
Related tert Standards
- 1-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-1H-pyrazole-4-carbaldehyde (CAS 2209077-68-7)
- 4-((tert-Butyldimethylsilyl)oxy)-2-fluorobenzaldehyde (CAS 175968-16-8)
- 3-(((Tert-butyldimethylsilyl)oxy)methyl)-5-methoxypyridine (CAS 1045855-62-6)
- (6-(((tert-Butyldimethylsilyl)oxy)methyl)pyridin-2-yl)methanol (CAS 150058-64-3)
- tert-Butyldimethylsilyl 2-bromoacetate (CAS 480439-46-1)
- (5-((tert-Butyldimethylsilyl)oxy)pyridin-3-yl)boronic acid (CAS 1309982-37-3)
- (5-(((Tert-butyldimethylsilyl)oxy)methyl)furan-2-yl)boronic acid (CAS 1072952-55-6)
- 1-[(tert-Butyldimethylsilyl)oxy]-2-methyl-2-acetoxypropanol-d6 (CAS 1184976-30-4)
Recommended Standards
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- Trimethoxy(4-phenylbutyl)silane (CAS 152958-91-3)
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- Ethoxydiphenyl(vinyl)silane (CAS 17933-85-6)
- 5-((3-Amino-5-carbamoyl-4-methylphenyl)(methyl)amino)-N,2-dimethylbenzamide (CAS 1249563-99-2)
- 5-Ethyl-5-(1-methyl-1h-pyrazol-4-yl)imidazolidine-2,4-dione (CAS 1423029-14-4)
- 2-Cyano-N-(3,4-dimethylphenyl)-3-(4-hydroxy-3-methoxyphenyl)propanamide (CAS 1260943-79-0)
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- 2-(M-tolyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine (CAS 887200-95-5)
- (2E)-2-(4-Bromobenzenesulfonyl)-3-(5,7-dimethyl-4-oxo-4H-chromen-3-yl)prop-2-enenitrile (CAS 1025255-71-3)
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