2-(6-Fluorobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 1394973-17-1
| CAS No. | 1394973-17-1 |
| Molecular Formula | C14H16BFO3 |
| Molecular Weight | 262.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(6-Fluorobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.
2-(6-Fluorobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1394973-17-1) is a high-purity analytical reference standard with the molecular formula C14H16BFO3 and a molecular weight of 262.08 g/mol.
The molecular framework of 2-(6-Fluorobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C14H16BFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(6-Fluorobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H16BFO3 |
| Molecular Weight | 262.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Fluorobenzofuran Standards
- 2-(5-Fluorobenzofuran-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1510689-13-0)
- 2-(6-Fluorobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628703-38-7)
- 2-(4-Fluorobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628703-39-8)
- 7-Fluorobenzofuran-6-boronic Acid Pinacol Ester (CAS 1628703-42-3)
- (4-Fluorobenzofuran-2-yl)boronic acid pinacol ester (CAS 2121514-66-5)
- 2-(6-fluorobenzofuran-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2614262-12-1)
- 4-Fluorobenzofuran-7-boronic acid pinacol ester (CAS 2121511-48-4)
- Ethyl 2-(5-fluorobenzofuran-3-yl)acetate (CAS 796851-84-8)
Recommended Standards
- Ethyl 3-amino-2-bromo-5-fluorobenzoate (CAS 1343992-94-8)
- methyl 3-amino-5-bromo-6-fluoro-2-methylbenzoate (CAS 1403258-33-2)
- Ethyl 3-amino-4-bromo-5-fluorobenzoate (CAS 1343597-84-1)
- 2,3,5,6-Tetrafluorophenyl trifluoroacetate (CAS 142685-25-4)
- 3-(2-(3-Amino-1h-pyrazol-1-yl)ethyl)oxazolidin-2-one (CAS 1341373-68-9)
- 6-Isopropyl-2-methyl-5-oxo-5,6-dihydro-1,6-naphthyridine-3-carboxylic acid (CAS 1232782-60-3)
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- Bis(2-methoxyethyl)aminosulfur Trifluoride (CAS 202289-38-1)
- 4-Chloro-5-(4-(trifluoromethyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1072027-17-8)
- 5-Ethyl-2-(3,5-difluorophenyl)-5-methylmorpholine (CAS 1516543-18-2)
- 4-(5-Bromonicotinamido)butanoic acid (CAS 337488-88-7)
- 4-Amino-1-oxa-9-thiaspiro[5.5]Undecane 9,9-dioxide (CAS 1342482-19-2)
- 5-(4-Fluoro-3-nitrophenyl)-2H-tetrazole (CAS 328244-35-5)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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