4-Chloro-5-fluorobenzene-1,2-diamine CAS 139512-70-2
| CAS No. | 139512-70-2 |
| Molecular Formula | C6H6ClFN2 |
| Molecular Weight | 160.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-Chloro-5-fluorobenzene-1,2-diamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-Chloro-5-fluorobenzene-1,2-diamine (CAS 139512-70-2), molecular formula C6H6ClFN2 and molecular weight 160.58 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-5-fluorobenzene-1,2-diamine (C6H6ClFN2) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H6ClFN2 |
| Molecular Weight | 160.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-3-fluorobenzene-1,2-diamine (CAS 1106717-48-9)
- (2-Chloro-3-fluorophenyl)hydrazine (CAS 1138218-48-0)
- (3-Chloro-2-fluoropyridin-4-yl)methanamine (CAS 1149588-74-8)
- 2-Chloro-5-fluoro-4,6-dimethylpyrimidine (CAS 1192479-36-9)
- (2-Chloro-4-fluorophenyl)hydrazine (CAS 119452-65-2)
- (3-Chloro-5-fluoropyridin-2-yl)methanamine (CAS 1211578-98-1)
- 4-Chloro-5-fluoro-2,6-dimethylpyrimidine (CAS 1240622-52-9)
- (5-Chloro-3-fluoropyridin-2-yl)methanamine (CAS 1256791-14-6)
Recommended Standards
- (4-Chloro-6-fluoropyridin-3-yl)methanamine (CAS 1393567-27-5)
- 4-Chloro-6-fluorobenzene-1,3-diamine (CAS 1524-37-4)
- (4-Chloro-5-fluoropyridin-3-yl)methanamine (CAS 1393563-17-1)
- 3-Chloro-5-fluorobenzene-1,2-diamine (CAS 153505-33-0)
- Dodecyl Phthalate (CAS 21577-80-0)
- (R)-1-(4-fluoro-2-methylbenzyl)piperidin-3-amine (CAS 1222710-48-6)
- (2-Fluorophenyl)(2-((3-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone (CAS 851803-37-7)
- 3-[(2-Chlorophenyl)methyl]-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 119222-35-4)
- (S)-tert-Butyl 2-(((2-hydroxyethyl)thio)methyl)pyrrolidine-1-carboxylate (CAS 1353998-03-4)
- 4-[(2-Chloro-4-methoxyphenoxy)methyl]piperidinehydrochloride (CAS 1220035-87-9)
- 4-Chloro-2-cyclobutyl-6,7-dihydro-5h-cyclopenta[4,5]thieno[2,3-d]pyrimidine (CAS 1483172-25-3)
- Dicyclohexylamine benzyl (3R)-3-{[(benzyloxy)carbonyl](2-methoxy-2-oxoethyl)amino}pyrrolidine-1-carboxylate (CAS 1182723-69-8)
- AMG-337, >98% (HPLC) (CAS 1173699-31-4)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com