2-(5-Bromothiophen-2-yl)propanoic acid CAS 139547-22-1
| CAS No. | 139547-22-1 |
| Molecular Formula | C7H7BrO2S |
| Molecular Weight | 235.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(5-Bromothiophen-2-yl)propanoic acid (CAS 139547-22-1) is a high-purity analytical reference standard with the molecular formula C7H7BrO2S and a molecular weight of 235.10 g/mol.
The molecular framework of 2-(5-Bromothiophen-2-yl)propanoic acid (C7H7BrO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(5-Bromothiophen-2-yl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BrO2S |
| Molecular Weight | 235.10 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Bromothiophen Standards
- 3-(4-bromothiophen-2-yl)propanoic acid (CAS 1094428-25-7)
- 3-(3-Bromothiophen-2-yl)propanoic acid (CAS 1247800-38-9)
- 3-(5-Bromothiophen-3-yl)propanoic acid (CAS 1504095-39-9)
- 2-(4-Bromothiophen-3-yl)propanoic acid (CAS 1512630-28-2)
- 3-(4-Bromothiophen-3-yl)propanoic acid (CAS 1531051-34-9)
- 3-(2-Bromothiophen-3-yl)propanoic acid (CAS 1540152-03-1)
- 2-(3-Bromothiophen-2-yl)-1,3-dioxolane (CAS 56857-02-4)
- 2-(4-Bromothiophen-2-yl)-1,3-dioxolane (CAS 58267-85-9)
Recommended Standards
- methyl 2-bromo-2-(thiophen-3-yl)acetate (CAS 135660-91-2)
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- 2-(3-Bromo-5-methylthiophen-2-yl)acetic acid (CAS 1484993-84-1)
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