Moxifloxacin Impurity 77 CAS 1395471-18-7(Free Base)
| CAS No. | 1395471-18-7(Free Base) |
| Molecular Formula | C20H24FN3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Moxifloxacin Impurity 77 (C20H24FN3O3C2HF3O2) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Moxifloxacin Impurity 77 (CAS 1395471-18-7(Free Base), C20H24FN3O3C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Moxifloxacin Impurity 77 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24FN3O3 C2HF3O2 |
| Molecular Weight | 487.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Moxifloxacin Standards
- Moxifloxacin Impurity 62 (CAS 1003709-80-5)
- Moxifloxacin Impurity Ⅻ (CAS 100872-65-9)
- Moxifloxacin impurity 203 (CAS 1027303-55-4)
- Moxifloxacin EP Impurity B (CAS 1029364-73-5)
- Moxifloxacin Hydrochloride EP Impurity C (CAS 1029364-75-7)
- Moxifloxacin EP Impurity D (CAS 1029364-77-9)
- Moxifloxacin Impurity N45 (CAS 1042641-60-0)
- Moxifloxacin impurity 175 (CAS 104599-90-8)
Recommended Standards
- Zopiclone Impurity 15 (CAS 4180-30-7)
- Ursodeoxycholic Acid Impurity 65 (CAS CATO-C4X-142265)
- Butylphthalide Impurity 22 (CAS 14570-43-5)
- 1,5-Dimethoxy-4,8-dinitronaphthalene (CAS 303777-47-1)
- Spermine Bis (Nitric Oxide) Adduct (CAS 136587-13-8)
- 4-(Difluoromethoxy)-2-fluoro-1-methoxybenzene (CAS 1261567-55-8)
- Cefpirome Impurity 7 (CAS CATO-C4X-12077)
- 3,4-Dichloro-N-(4-chlorophenyl)benzenesulfonamide (CAS 640-59-5)
- 2-[4-(Trifluoromethyl)benzoyl]hydrazine-1-carbothioamide (CAS 10444-97-0)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
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