5-(2-(1-(Trifluoromethyl)cyclopropyl)-pyridin-4-yl)thiazol-2-amine CAS 1395492-77-9
| CAS No. | 1395492-77-9 |
| Molecular Formula | C12H10F3N3S |
| Molecular Weight | 285.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-(2-(1-(Trifluoromethyl)cyclopropyl)-pyridin-4-yl)thiazol-2-amine (CAS 1395492-77-9), a certified reference material (molecular formula C12H10F3N3S, MW 285.29 g/mol) for analytical method development and quality control.
5-(2-(1-(Trifluoromethyl)cyclopropyl)-pyridin-4-yl)thiazol-2-amine (C12H10F3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10F3N3S |
| Molecular Weight | 285.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
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- 8-[3-(trifluoromethyl)phenyl]-9-oxa-6-azaspiro[4.5]decane (CAS 1488005-16-8)
- 1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-one oxime (CAS 1114824-10-0)
- 1-(4-Methyl-2-(3-(trifluoromethyl)phenyl)thiazol-5-yl)ethan-1-one (CAS 896729-58-1)
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Recommended Standards
- 1-((4-Fluorophenyl)sulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid (CAS 1373247-82-5)
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- Benzyl 3,3-difluoro-5-(hydroxymethyl)piperidine-1-carboxylate (CAS 1356339-31-5)
- Ethyl 2-(4-acetylphenoxy)isonicotinate (CAS 1415719-67-3)
- 3-(Phenylcarbamoyl)bicyclo[2.2.1]Hept-5-ene-2-carboxylic acid (CAS 53193-34-3)
- 1-(4-Fluorophenyl)pentane-1,3-dione (CAS 38440-21-0)
- 2-Bromo-N1,N1-dimethylbenzene-1,4-diamine (CAS 860444-64-0)
- 4-Methoxy-6-(methylthio)-1,3,5-triazin-2-amine (CAS 30358-18-0)
- 1-OXA-SPIRO[4.5]DEC-7-ENE (CAS 87151-63-1)
- 2-Chloro-6-((3-methoxyphenyl)thio)-1H-purine (CAS 646510-28-3)
- Fmoc-l-beta-homoisoleucine (CAS 193954-27-7)
- (3-Fluoro-4-(thiomorpholinomethyl)phenyl)boronic acid (CAS 1334171-29-7)
- 1-(2-Methoxyethoxy)-3,3-dimethylbutan-2-one (CAS 1158069-79-4)
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