Carfilzomib Impurity N1 CAS 1396006-47-5
| CAS No. | 1396006-47-5 |
| Molecular Formula | C22H33N3O5 |
| Molecular Weight | 419.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 419.51 g/mol gives Carfilzomib Impurity N1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Carfilzomib Impurity N1 (CAS 1396006-47-5, C22H33N3O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Carfilzomib Impurity N1 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 419.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Carfilzomib Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H33N3O5 |
| Molecular Weight | 419.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Carfilzomib Standards
- Carfilzomib Impurity 80 (CAS 1545468-80-1)
- Carfilzomib Impurity 25 (CAS 15136-32-0)
- Carfilzomib Impurity 82 (CAS CATO-C4X-102282)
- Carfilzomib Impurity 71 (CAS 868539-98-4)
- Carfilzomib Impurity 32 (CAS CATO-C4X-102232)
- Carfilzomib Impurity 67 (CAS 70637-27-3)
- Carfilzomib Impurity 85 (CAS CATO-C4X-102285)
- Carfilzomib Impurity 81 (CAS CATO-C4X-102281)
Recommended Standards
- (4-bromo-8-methoxy-1-naphthyl)oxy-triisopropyl-silane (CAS 1319715-16-6)
- tert-butyl 4-(1-(tert-Butoxycarbonyl)piperidin-4-ylamino)-3,3-difluoropiperidine-1-carboxylate (CAS 1404196-59-3)
- Boc-NH-PEG6-propargyl (CAS 1262991-52-5)
- (S)-1-BOC-4-[2-(Cbz-Amino)isopentanoyl]piperazine 1420804-55-2 C22H33N3O5 V3167 (CAS 1420804-55-2)
- Suvorexant Impurity 1 (CAS 1030377-80-0)
- Argatroban Impurity 98 (CAS CATO-C4X-100798)
- Lasmiditan Impurity 4 (CAS 103640-16-0)
- 3,4-Dibromo-7-chloroquinoline (CAS 373384-15-7)
- Tris(tri-p-tolylphosphine)platinum (CAS 33937-28-9)
- N-Cyclopentyl-2-bromo-5-fluorobenzamide (CAS 951884-13-2)
- 2-(Trifluoromethyl)-1H-benzimidazole-6-carboxylic Acid (CAS 82791-93-3)
- N-[(-)-Jasmonoyl]-(L)-isoleucine (CAS 120330-93-0)
- 8-Bromo-2-chloro-6-methylquinoline (CAS 142219-60-1)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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