6-Chloro-2-phenylquinazoline-4(3H)-thione CAS 13961-52-9
| CAS No. | 13961-52-9 |
| Molecular Formula | C14H9ClN2S |
| Molecular Weight | 272.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-phenylquinazoline-4(3H)-thione (CAS 13961-52-9), molecular formula C14H9ClN2S and molecular weight 272.75 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Chloro-2-phenylquinazoline-4(3H)-thione (C14H9ClN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 272.75 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-2-phenylquinazoline-4(3H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9ClN2S |
| Molecular Weight | 272.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- (S)-2-Amino-N-(2-chloro-6-fluorobenzyl)-N-isopropylpropanamide (CAS 1354018-98-6)
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- 2-(2-Chloropyridin-3-yl)-4-phenylthiazole (CAS 1431728-44-7)
- 2-(2-((Tetrahydro-2h-pyran-4-yl)oxy)ethoxy)ethane-1-sulfonyl chloride (CAS 1343631-98-0)
- 2-Methoxy-3,4-dimethyl-1-nitrobenzene (CAS 99321-71-8)
- 3-((tert-Butoxycarbonyl)amino)-3-(thiazol-2-yl)propanoic acid (CAS 1696030-41-7)
- 2-​Formamidoacetamide (CAS 4238-57-7)
- 2-Chloro-5-nitrobenzyl 4-methoxybenzoate (CAS 331460-06-1)
- JIB-04 (CAS 199596-05-9)
- ethyl [3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]acetate (CAS 1015781-16-4)
- Fmoc-Dap-OH (CAS 181954-34-7)
- 2-methyl-4-(1-methylcyclopropoxy)-1-nitrobenzene (CAS 1626355-70-1)
- 3-methyloxetane-3-carbaldehyde (CAS 99419-31-5)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
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