(3-Bromophenyl)(7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)methanone CAS 1396844-56-6
| CAS No. | 1396844-56-6 |
| Molecular Formula | C15H18BrNO3 |
| Molecular Weight | 340.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3-Bromophenyl)(7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)methanone (CAS 1396844-56-6) is a high-purity analytical reference standard with the molecular formula C15H18BrNO3 and a molecular weight of 340.21 g/mol.
The molecular framework of (3-Bromophenyl)(7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)methanone (C15H18BrNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3-Bromophenyl)(7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H18BrNO3 |
| Molecular Weight | 340.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- N-Benzyl-4-bromonaphthalene-1-carboxamide (CAS 1375068-64-6)
- tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate (CAS 1398609-80-7)
- 1-[2-(Bromomethyl)-1,3-dioxolan-2-yl]-N-(phenylmethyl)cyclopropanecarboxamide (CAS 147011-41-4)
- 1-[(5-Bromothien-2-yl)sulphonyl]pyrrolidine-2-carboxylic acid (CAS 1301738-60-2)
- 4-(4-Fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)piperazine-1-carboxamide (CAS 866137-30-6)
- Methyl 3-(3-Hydroxy-4-methoxyphenyl)propanoate (CAS 129150-61-4)
- 4-Amino-5-(difluoromethyl)-3-nitropicolinonitrile (CAS 1805928-64-6)
- Methyl N-(5-chloro-2-methylphenyl)-N-(phenylsulfonyl)glycinate (CAS 418804-73-6)
- N-methyl-4,5-dihydro-1,3-oxazol-2-amine (CAS 2214-70-2)
- N-(3-Cyano-2-cyclopropoxyphenyl)methanesulfonamide (CAS 1243351-67-8)
- Relebactam Impurity 84 (CAS 1174069-42-1)
- 2-Amino-4-(4-chloro-5-methyl-1h-pyrazol-1-yl)-2-methylbutanoic acid (CAS 1342081-18-8)
- 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 2-methylbenzoate (CAS 477889-63-7)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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