5-Chloro-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)thiophene-2-carboxamide CAS 1396875-27-6
| CAS No. | 1396875-27-6 |
| Molecular Formula | C13H10ClN3OS |
| Molecular Weight | 291.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)thiophene-2-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)thiophene-2-carboxamide (CAS 1396875-27-6) is a high-purity analytical reference standard with the molecular formula C13H10ClN3OS and a molecular weight of 291.76 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)thiophene-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10ClN3OS |
| Molecular Weight | 291.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-6-(3-methoxyphenyl)-2-(methylthio)pyrimidine-5-carbonitrile (CAS 128666-82-0)
- 1-((5-Chloro-4-hydrazinylpyridin-3-yl)sulfonyl)piperazine (CAS 1352507-45-9)
- 2-Chloro-n-[4-(1h-indol-3-yl)-1,3-thiazol-2-yl]acetamide (CAS 19750-29-9)
- 2-(4-(4-Chloro-1H-pyrazol-1-yl)benzyl)isothiazol-3(2H)-one (CAS 918108-07-3)
- N-[5-(2-Chloro-benzyl)-thiazol-2-yl]-2-cyano-acetamide (CAS 307514-08-5)
- 2-(((3-Chloro-2-methylphenyl)amino)methyl)-6-ethoxyphenol (CAS 1019535-57-9)
- 2-(((2-Chloro-4-methylphenyl)amino)methyl)-6-ethoxyphenol (CAS 1037137-94-2)
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Recommended Standards
- (E)-{[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene}(methoxy)amine (CAS 338404-41-4)
- 2-{[4-(chloromethyl)-1,3-thiazol-2-yl]methyl}-1,2-dihydrophthalazin-1-one (CAS 1094436-42-6)
- 1-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-N-(4-methoxyphenyl)methanimine (CAS 338976-73-1)
- 5-(1-(3-Chlorophenyl)-5-methyl-1H-pyrazol-4-yl)-4H-1,2,4-triazole-3-thiol (CAS 1019090-30-2)
- 2-(4-OXAZOL-2-YL-BENZENESULFONYLAMINO)-3-({1-[3-(1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINO)-PROPYL]-1H-INDAZOLE-5-CARBONYL}-AMINO)-PROPIONIC ACID (CAS 1231023-28-1)
- 2-Oxa-7-azaspiro[4.4]nonane hydrochloride (CAS 1419590-58-1)
- 1-Chloro-2-isothiocyanato-3,5-dimethylbenzene (CAS 871909-88-5)
- N-(2,3-Difluorobenzyl)-1-(1-methyl-1H-pyrazol-3-yl)methanamine hydrochloride (CAS 1856070-92-2)
- 1-Benzyl-6,6-difluoro-1,4-diazepane (CAS 1780938-05-7)
- Tert-butyl 5,5-difluoro-7-oxa-2-azaspiro[3.5]Nonane-2-carboxylate (CAS 2306263-90-9)
- 3-Cyclopropoxy-2-nitrobenzenesulfonamide (CAS 1243401-66-2)
- 3-(sec-Butyl)-6-isopropylpiperazine-2,5-dione (CAS 104068-43-1)
- 4-Acetyl-2-amino-5-methylfuran-3-carbonitrile (CAS 108129-35-7)
- Custom peptides (CAS CATO-CPTD788509)
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