Amphotericin B CAS 1397-89-3
| CAS No. | 1397-89-3 |
| Molecular Formula | C47H73NO17 |
| Molecular Weight | 924.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Amphotericin B is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Amphotericin B (CAS 1397-89-3), a certified reference material (molecular formula C47H73NO17, MW 924.08 g/mol) for analytical method development and quality control.
Structurally, Amphotericin B (C47H73NO17) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 924.08 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Amphotericin B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C47H73NO17 |
| Molecular Weight | 924.08 g/mol |
| Purity | >80% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Amphotericin Standards
- Amphotericin B Impurity 23 (CAS CATO-C4X-184423)
- Amphotericin B Impurity 19 (CAS CATO-C4X-184419)
- Amphotericin B EP Impurity A (CAS 1405-32-9)
- Amphotericin B Impurity 16 (CAS CATO-C4X-184416)
- Amphotericin B Impurity 24 (CAS CATO-C4X-184424)
- Amphotericin B Impurity 7 (CAS CATO-C4X-18447)
- Amphotericin B Impurity 17 (CAS CATO-C4X-184417)
- Amphotericin B-13C6 (CAS 1397-89-3 (non-labelled))
Recommended Standards
- Chlorohydridotris(triphenylphosphine)ruthenium(II) toluene adduct (CAS 55102-19-7)
- Azido-PEG20-alcohol (CAS 1637297-21-2)
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- Mercury(II) silver iodide (CAS 7784-03-4)
- 2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one hydrochloride (CAS 95130-23-7)
- Diallate (CAS 2303-16-4)
- Miglustat Impurity A (CAS 253328-56-2)
- 2,2,2-Trifluoro-1-(2-hydroxy-5-methylphenyl)ethan-1-one (CAS 70978-57-3)
- Methyl 1-phenyl-1H-pyrrole-2-carboxylate (CAS 35524-54-0)
- 1-Methoxy-N-(3-phenoxybenzyl)propan-2-amine hydrobromide (CAS 1609400-32-9)
- 6-Chloro-2,3-dihydro-4H-pyrano[2,3-b]pyridin-4-one (CAS 122433-49-2)
- 3-(4-Chlorophenyl)-5-((4-nitrobenzyl)thio)-4-(p-tolyl)-4H-1,2,4-triazole (CAS 477330-92-0)
- Glycopyrronium Bromide Impurity 20 (CAS CATO-C4X-181720)
- Allo-Thr7-Tirzepatide (CAS CATO-CPTD788933)
Why CATO?
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