6-Fluoro-2-phenylquinazoline CAS 1399327-71-9
| CAS No. | 1399327-71-9 |
| Molecular Formula | C14H9FN2 |
| Molecular Weight | 224.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Fluoro-2-phenylquinazoline (CAS 1399327-71-9) is a high-purity analytical reference standard with the molecular formula C14H9FN2 and a molecular weight of 224.23 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 6-Fluoro-2-phenylquinazoline is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 224.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H9FN2 |
| Molecular Weight | 224.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Ethyl 3-(4-fluoro-2-methylphenyl)-3-oxopropanoate (CAS 1397193-30-4)
- 5-Fluoro-7,8-dimethoxy-3,4-dihydronaphthalen-1(2H)-one (CAS 140377-92-0)
- 1-((2-Fluorophenoxy)methyl)cyclobutanecarboxylic acid (CAS 1387574-26-6)
- Methyl 5-(3-fluorophenyl)-5-oxopentanoate (CAS 1443351-25-4)
- rac-(3S,8aR)-hexahydro-1H-pyrrolo[2,1-c]morpholine-3-carbohydrazide (CAS 1909294-89-8)
- Rifapentine-15N (CAS CATO-C4X-19599)
- 3-(2-Azepanyl)-n,n-dimethylaniline oxalate (CAS 1177272-51-3)
- 2-(Prop-2-yn-1-ylsulfanyl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 306976-48-7)
- 5-Nitro-2-(phenylselanyl)phenylboronic acid (CAS 2377605-98-4)
- 3-Bromo-5-fluoro-4-nitroaniline (CAS 1805109-05-0)
- 5-((2-Chloropyrimidin-4-yl)(methyl)amino)-2-methylbenzoic acid (CAS 1394349-77-9)
- 2-Cyclopropyl-4-quinolinecarboxylic acid hydrate (CAS 1982213-91-1)
- 2-Iodo-2-3-O-isopropylideneadenosine (CAS 141018-25-9)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
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