2-(2-Nitrophenyl)-5-oxotetrahydrofuran-3-carboxylic acid CAS 1399653-10-1
| CAS No. | 1399653-10-1 |
| Molecular Formula | C11H9NO6 |
| Molecular Weight | 251.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2-Nitrophenyl)-5-oxotetrahydrofuran-3-carboxylic acid (CAS 1399653-10-1), molecular formula C11H9NO6 and molecular weight 251.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2-Nitrophenyl)-5-oxotetrahydrofuran-3-carboxylic acid (C11H9NO6) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-Nitrophenyl)-5-oxotetrahydrofuran-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9NO6 |
| Molecular Weight | 251.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Nitrophenyl Standards
- Methyl 4-(2-nitrophenyl)-2,4-dioxobutanoate (CAS 57446-03-4)
- Methyl 4-(3-nitrophenyl)-2,4-dioxobutanoate (CAS 345617-18-7)
- Methyl 4-(4-nitrophenyl)-2,4-dioxobutanoate (CAS 39757-36-3)
- (E)-4-(2-(2-nitrophenyl)hydrazinyl)-4-oxobut-2-enoic acid (CAS 39704-29-5)
- (E)-4-(2-(4-nitrophenyl)hydrazinyl)-4-oxobut-2-enoic acid (CAS 39704-31-9)
- 4-(4-Nitrophenyl)-1,2,3-thiadiazole-5-carboxylic acid (CAS 1481380-50-0)
- 4-(3-Nitrophenyl)-1,2,3-thiadiazole-5-carboxylic acid (CAS 1481665-11-5)
- Ethyl 4-(3-nitrophenyl)-3-oxobutanoate (CAS 116904-71-3)
Recommended Standards
- (2-Fluoro-4-(pentafluoro-λ6-sulfanyl)phenyl)methanamine (CAS 1240257-86-6)
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- (3-Fluoro-5-(pentafluoro-lambda6-sulfanyl)phenyl)methanamine (CAS 1240257-73-1)
- Methyl (3z)-4-hydroxy-4-(3-nitrophenyl)-2-oxobut-3-enoate (CAS 151646-59-2)
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- 2-(Cyclooctylamino)propan-1-ol (CAS 1153893-81-2)
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- [1-(6-chloropyrimidin-4-yl)pyrrolidin-2-yl]methanol (CAS 1251146-77-6)
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