Methyl 2-bromo-2-(4-fluorophenyl)propanoate CAS 1399656-48-4
| CAS No. | 1399656-48-4 |
| Molecular Formula | C10H10BrFO2 |
| Molecular Weight | 261.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 2-bromo-2-(4-fluorophenyl)propanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 2-bromo-2-(4-fluorophenyl)propanoate (CAS 1399656-48-4), molecular formula C10H10BrFO2 and molecular weight 261.09 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, Methyl 2-bromo-2-(4-fluorophenyl)propanoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 261.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10BrFO2 |
| Molecular Weight | 261.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
Related Methyl Standards
- Ethyl 2-bromo-2-(2-fluorophenyl)acetate (CAS 100638-28-6)
- 6-Bromo-2-fluoro-3-propoxybenzaldehyde (CAS 1114809-09-4)
- 2-Bromo-1-(2-fluoro-4-methoxyphenyl)propan-1-one (CAS 1156358-86-9)
- Ethyl 2-(2-Bromo-5-fluorophenyl)acetate (CAS 1214910-61-8)
- 2-(5-Bromo-2-fluorophenyl)-2-(methylamino)acetamide (CAS 1218352-01-2)
- 2-(3-Bromo-4-fluorophenyl)-2-(methylamino)acetamide (CAS 1218749-87-1)
- Ethyl 2-(3-bromo-4-fluorophenyl)acetate (CAS 1228689-75-5)
- 3-(4-Bromo-2-fluorophenyl)-2-methylpropanoic acid (CAS 1247888-93-2)
Recommended Standards
- Ethyl 4-bromo-2-fluoro-3-methylbenzoate (CAS 1394003-97-4)
- 3-(4-Bromo-3-methoxyphenyl)-3-fluorooxetane (CAS 1443379-84-7)
- Propan-2-yl 5-bromo-2-fluorobenzoate (CAS 1369403-80-4)
- Ethyl 5-bromo-2-fluoro-4-methylbenzoate (CAS 1445967-31-6)
- tert-Butyl (4aR,8aR)-octahydro-1,6-naphthyridine-6(2H)-carboxylate (CAS 616875-91-3)
- (6-chloro-5-fluoro-2-methyl-1H-indol-3-yl) acetate (CAS 2627980-81-6)
- 4-chloro-6-fluoropyridin-3-ol (CAS 1227578-00-8)
- ((1R,3S)-3-((thietan-3-ylamino)methyl)cyclohexyl)methanol (CAS 1846634-29-4)
- Tenofovir disoproxil Impurity 141 (CAS CATO-C4X-1076141)
- Ceftriaxone EP Impurity C (CAS CATO-C4X-116342)
- Benzyl (1-(phenylsulfonyl)butyl)carbamate (CAS 860788-40-5)
- 4-Bromo-1-((tetrahydro-2H-pyran-2-yl)methyl)-1H-pyrazole (CAS 1183588-29-5)
- Sunitinib Impurity 72 (CAS CATO-C4X-133372)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
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