tert-Butyl (5-(trifluoromethyl)pyridin-2-yl)carbamate CAS 1399664-49-3
| CAS No. | 1399664-49-3 |
| Molecular Formula | C11H13F3N2O2 |
| Molecular Weight | 262.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures tert-Butyl (5-(trifluoromethyl)pyridin-2-yl)carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies tert-Butyl (5-(trifluoromethyl)pyridin-2-yl)carbamate (CAS 1399664-49-3), a certified reference material (molecular formula C11H13F3N2O2, MW 262.23 g/mol) for analytical method development and quality control.
tert-Butyl (5-(trifluoromethyl)pyridin-2-yl)carbamate (C11H13F3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H13F3N2O2 |
| Molecular Weight | 262.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl N-[4-(trifluoromethyl)pyridin-3-yl]carbamate (CAS 1392804-92-0)
- Methyl 4-isopropoxy-3-(trifluoromethyl)benzoate (CAS 1401511-01-0)
- 2-((3-(Trifluoromethyl)phenyl)amino)benzonitrile (CAS 13481-62-4)
- 5-((2-Fluorobenzyl)oxy)-2-hydroxybenzoic acid (CAS 1415010-89-7)
- 2-ethenyl-1,1-bis(fluoranyl)cyclopropane 2-ethenyl-1,1-difluorocyclopropane 694-34-8 A836495 (CAS 694-34-8)
- 5-Bromo-2-chloro-N-methoxy-N-methylnicotinamide (CAS 885223-63-2)
- 2-[(Cyanomethyl)thio]acetonitrile (CAS 5848-75-9)
- 1-Methyl-3-piperidin-3-yl-1H-pyrazolo[3,4-b]pyridine dihydrochloride (CAS 1361113-44-1)
- 2,6-Di(thiophen-2-yl)aniline (CAS 1415512-67-2)
- Tert-butyl 3a-methylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (CAS 2044713-96-2)
- N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine-4-sulfonamide (CAS 914606-94-3)
- 4-(2,2-Dicyanovinyl)phenyl 4-(benzo[d]oxazol-2-yl)benzoate (CAS 66487-16-9)
- 1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]ethan-1-amine (CAS 933698-96-5)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com