Piperazine Impurity 24 CAS 140-79-4
| CAS No. | 140-79-4 |
| Molecular Formula | C4H8N4O2 |
| Molecular Weight | 144.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Piperazine Impurity 24.
CATO supplies Piperazine Impurity 24 (CAS 140-79-4), a pharmacopoeial impurity reference standard (molecular formula C4H8N4O2, MW 144.13 g/mol) used for the identification and quantification of trace impurities in APIs.
Piperazine Impurity 24 (C4H8N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Piperazine Impurity 24 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H8N4O2 |
| Molecular Weight | 144.13 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
Related Piperazine Standards
- methyl piperazine-2-carboxylate (CAS 2758-98-7)
- Piperazine-1-carbohydrazide (CAS 99839-43-7)
- Piperazine Impurity 14 (CAS 58226-19-0)
- Piperazine Impurity 43 (CAS 50606-31-0)
- (E)-piperazine-1-carbohydrazonamide (CAS 683743-32-0)
- piperazine-1-carbothioamide (CAS 54147-47-6)
- 1-(2-Butyl)-piperazine (CAS 34581-21-0)
- 2-Butyl-piperazine (CAS 90203-03-5)
Recommended Standards
- 3,4-Dideoxyglucosone-3-ene (CAS 252006-38-5)
- Furacillin impurity 2 (CAS CATO-C4X-28052)
- Dimethyl Maleate (CAS 624-48-6)
- N-Nitroso Proline (CAS 2571-28-0)
- Terbutaline Impurity 75 (CAS CATO-C4X-118375)
- Furosemide Impurity 39 (CAS CATO-C4X-140239)
- Sitagliptin Impurity 128 (CAS CATO-C4X-1144128)
- Ethyl 2-amino-4-methylbenzoate (CAS 64818-80-0)
- Pyrazolo[1,5-b]pyridazine (CAS 35731-27-2)
- 3-(1,1-Difluoroethyl)aniline hydrochloride (CAS 1803593-33-0)
- Lapatinib Impurity 5 (CAS 179246-45-8)
- N-(2-(2-(4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide methanesulfonate hydrate (CAS 2097125-58-9)
- 1-Acetyl-1,2,3,4-tetrahydroquinolin-7-amine hydrochloride (CAS 1417355-08-8)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com