tert-Butyl 3,3-Difluoro-4-formyl-4-methylpiperidine-1-carboxylate CAS 1400764-63-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1400764-63-7
Molecular FormulaC12H19F2NO3
Molecular Weight263.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 3,3-Difluoro-4-formyl-4-methylpiperidine-1-carboxylate CAS 1400764-63-7 chemical structure

Description

The occurrence of tert-Butyl 3,3-Difluoro-4-formyl-4-methylpiperidine-1-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies tert-Butyl 3,3-Difluoro-4-formyl-4-methylpiperidine-1-carboxylate (CAS 1400764-63-7), a certified reference material (molecular formula C12H19F2NO3, MW 263.28 g/mol) for analytical method development and quality control.

Structurally, tert-Butyl 3,3-Difluoro-4-formyl-4-methylpiperidine-1-carboxylate (C12H19F2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 263.28 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl 3,3-Difluoro-4-formyl-4-methylpiperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H19F2NO3
Molecular Weight263.28 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms1

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