7-Bromo-2-chloro-3H-imidazo[4,5-b]pyridine CAS 1401687-52-2
| CAS No. | 1401687-52-2 |
| Molecular Formula | C6H3BrClN3 |
| Molecular Weight | 232.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Bromo-2-chloro-3H-imidazo[4,5-b]pyridine.
CATO supplies 7-Bromo-2-chloro-3H-imidazo[4,5-b]pyridine (CAS 1401687-52-2), a certified reference material (molecular formula C6H3BrClN3, MW 232.47 g/mol) for analytical method development and quality control.
The molecular framework of 7-Bromo-2-chloro-3H-imidazo[4,5-b]pyridine (C6H3BrClN3) is characterized by a nitrile group, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrClN3 |
| Molecular Weight | 232.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
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Recommended Standards
- 6-Bromo-3-chloro-1H-pyrazolo[4,3-b]pyridine (CAS 1391123-68-4)
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- 6-Bromo-7-chloro-1H-benzo[d][1,2,3]triazole (CAS 1388044-33-4)
- 7-Bromo-2-chloro-3H-imidazo[4,5-c]pyridine (CAS 1401687-55-5)
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- 7-(Ethylamino)-4-methyl-2H-chromen-2-one (CAS 28821-18-3)
- 1-((4-Ethoxypyridin-3-yl)sulfonyl)piperazine (CAS 1352514-58-9)
- Exenatide (CAS 141758-74-9)
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