4-Fluoro-2-(2-(trifluoromethyl)oxetan-2-yl)phenol CAS 1402004-66-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1402004-66-3
Molecular FormulaC10H8F4O2
Molecular Weight236.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Fluoro-2-(2-(trifluoromethyl)oxetan-2-yl)phenol CAS 1402004-66-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Fluoro-2-(2-(trifluoromethyl)oxetan-2-yl)phenol.

4-Fluoro-2-(2-(trifluoromethyl)oxetan-2-yl)phenol (CAS 1402004-66-3), molecular formula C10H8F4O2 and molecular weight 236.16 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Fluoro-2-(2-(trifluoromethyl)oxetan-2-yl)phenol (C10H8F4O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Fluoro-2-(2-(trifluoromethyl)oxetan-2-yl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H8F4O2
Molecular Weight236.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing

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Why CATO?