4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(p-tolyl)pyridine CAS 1402172-12-6
| CAS No. | 1402172-12-6 |
| Molecular Formula | C18H22BNO2 |
| Molecular Weight | 295.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(p-tolyl)pyridine (CAS 1402172-12-6), molecular formula C18H22BNO2 and molecular weight 295.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(p-tolyl)pyridine (C18H22BNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H22BNO2 |
| Molecular Weight | 295.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Tetramethyl Standards
- 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-amine (CAS 1008788-39-3)
- 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyridine (CAS 1192588-89-8)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(o-tolyl)pyridine (CAS 1402172-14-8)
- Ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridin-1(2H)-yl)acetate (CAS 1613697-85-0)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9a-dihydro-4aH-carbazole (CAS 871125-67-6)
- 2-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2094504-02-4)
- 4-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-1,4-benzoxazin-2-one (CAS 2653202-04-9)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide (CAS 1607838-33-4)
Recommended Standards
- tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-pyrrole-1-carboxylate (CAS 1401165-14-7)
- 3-Bromo-N-(4-(dimethylamino)but-2-yn-1-yl)benzamide (CAS 1396802-57-5)
- 6-Bromo-2-(piperidin-3-yl)isoindolin-1-one (CAS 1443286-04-1)
- 5-Bromo-2-(cyclohexylmethoxy)nicotinonitrile (CAS 1356073-62-5)
- Methyl 2-((2-(1H-imidazol-1-yl)ethyl)thio)-6-chloro-1H-benzo[d]imidazole-5-carboxylate (CAS 1446718-30-4)
- 3-[(2-Bromoacetyl)amino]-N-butylbenzamide (CAS 1138442-77-9)
- 4-(4-Chloro-3-methylphenoxy)-2-(trifluoromethyl)aniline (CAS 946741-39-5)
- Tert-butyl 4-(((2-aminophenyl)amino)methyl)piperidine-1-carboxylate (CAS 600725-25-5)
- N-(1,3-thiazol-4-ylmethyl)aniline (CAS 15869-08-6)
- 1-(4-Aminophenyl)-3-(2,6-dichlorophenyl)prop-2-en-1-one (CAS 899017-43-7)
- 3-chloropropyl 2-hydroxypropanoate (CAS 1314921-33-9)
- 4-Bromo-2-(3,3-difluoroazetidin-1-yl)benzaldehyde 1779127-23-9 (CAS 1779127-23-9)
- 6-Bromo-4-(cyanomethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1805441-91-1)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
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