5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(o-tolyl)thiazole CAS 1402173-89-0
| CAS No. | 1402173-89-0 |
| Molecular Formula | C16H20BNO2S |
| Molecular Weight | 301.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(o-tolyl)thiazole (CAS 1402173-89-0), molecular formula C16H20BNO2S and molecular weight 301.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(o-tolyl)thiazole (C16H20BNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H20BNO2S |
| Molecular Weight | 301.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Tetramethyl Standards
- 2-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thiazole (CAS 857283-68-2)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidin-2-one (CAS 1007346-42-0)
- 1-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (CAS 1181691-47-3)
- N-(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropyl)acetamide (CAS 1218789-39-9)
- 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (CAS 937591-82-7)
- 1-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-1(2H)-yl)ethanone (CAS 2170897-51-3)
- 1-(7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethanone (CAS 937591-29-2)
- N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutanecarboxamide (CAS 2246657-11-2)
Recommended Standards
- 5-Bromo-6-(tert-butyl)-4-methoxythieno[2,3-d]pyrimidine (CAS 2764889-44-1)
- 1,3-Dinitrodibenzo[b,f][1,4]oxazepin-11(10H)-one (CAS 309735-46-4)
- 2-(Benzo[d][1,3]selenazol-2-yl)-1-(pyridin-3-yl)ethanone (CAS 62729-11-7)
- 1,4,5-Trihydroxy-8-nitroanthracene-9,10-dione (CAS 39003-38-8)
- Dimethyl 1,2,2-trimethylcyclopentane-1,3-dicarboxylate (CAS 7282-27-1)
- 1,1-Difluoro-1-butene (CAS 407-09-0)
- 4-(((2,6-Dichlorophenyl)thio)methyl)-1-methyl-3-(trifluoromethyl)-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole (CAS 318959-17-0)
- 2-amino-7-methyl-3,4-dihydroquinazolin-4-one (CAS 1026727-75-2)
- (2-Bromo-6-fluoro-3-methoxyphenyl)(methyl)sulfane (CAS 2090548-28-8)
- (9H-Fluoren-9-yl)methanamine hydrochloride (CAS 34221-61-9)
- (1R,3s,5S)-6,6-Difluorobicyclo[3.1.0]hexane-3-carbaldehyde (CAS 2126913-33-3)
- 5,6-Dihydro-4H-cyclopenta[d]oxazol-6-ol (CAS 2098584-51-9)
- (2-(Benzyloxy)naphthalen-1-yl)methanol (CAS 217176-35-7)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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