2-(4-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole CAS 1402227-63-7
| CAS No. | 1402227-63-7 |
| Molecular Formula | C16H20BNO3S |
| Molecular Weight | 317.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1402227-63-7), molecular formula C16H20BNO3S and molecular weight 317.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (C16H20BNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H20BNO3S |
| Molecular Weight | 317.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methoxyphenyl Standards
- 2-(2-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1402227-61-5)
- 4-(3-Methoxyphenyl)-3-methyl-8-(trifluoromethyl)quinoline (CAS 854774-90-6)
- 6-(4-Methoxyphenyl)-5-phenylfuro[2,3-d]pyrimidin-4-amine (CAS 14774-66-4)
- (2Z)-2-{[(4-methoxyphenyl)amino]methylidene}-1H,2H-naphtho[2,1-b]furan-1-one (CAS 338415-30-8)
- 1-{7-[(E)-2-(4-methoxyphenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-1H-pyrrole (CAS 303146-10-3)
- 3-(((2-Methoxyphenyl)amino)methylene)-1,5-dioxaspiro[5.5]undecane-2,4-dione (CAS 384357-00-0)
- 3-(((3-Methoxyphenyl)amino)methylene)-1,5-dioxaspiro[5.5]undecane-2,4-dione (CAS 369394-57-0)
- 4-(4-Methoxyphenyl)-6-(methylamino)-2-(pyridin-2-yl)pyrimidine-5-carbonitrile (CAS 320418-93-7)
Recommended Standards
- 2-Chloro-4-(2-chlorophenyl)-6-methyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1707372-28-8)
- 3-[4-(3,4-Dichlorobenzyl)piperazin-1-yl]propanoic acid (CAS 1155622-26-6)
- 2-Chloro-4-(4-chlorophenyl)-6-methyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1710661-48-5)
- (4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(thiazol-2-yl)methanol (CAS 1073371-73-9)
- 1-(4-Methoxy-9H-pyrido[3,4-b]indol-1-yl)ethanone (CAS 65236-63-7)
- 2,3-Dibromo-6-fluorobenzyl bromide (CAS 1803817-09-5)
- 53116-81-7 Tetrakis(N,N,N-trimethylmethanaminium) orthosilicate DTXSID50746209 (CAS 53116-81-7)
- 2-Chloro-8-methoxy-4-methylquinazoline (CAS 953039-90-2)
- 1-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidine (CAS 884507-21-5)
- 5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulene-2-carbonitrile (CAS 74220-59-0)
- 2-Methyloxolane-3-carbohydrazide (CAS 1502082-16-7)
- Sodium 1-(tert-butoxycarbonyl)-4-oxopiperidine-3-carboxylate (CAS 2007909-56-8)
- 5-(Bromomethyl)-2-fluoro-4-iodopyridine (CAS 1034466-98-2)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
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