3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(3,4-difluorophenyl)thiophen-2-yl)boronate CAS 1402227-87-5
| CAS No. | 1402227-87-5 |
| Molecular Formula | C16H19BF2O3S |
| Molecular Weight | 340.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 340.19 g/mol gives 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(3,4-difluorophenyl)thiophen-2-yl)boronate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(3,4-difluorophenyl)thiophen-2-yl)boronate (CAS 1402227-87-5), molecular formula C16H19BF2O3S and molecular weight 340.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(3,4-difluorophenyl)thiophen-2-yl)boronate (C16H19BF2O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(3,4-difluorophenyl)thiophen-2-yl)boronate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19BF2O3S |
| Molecular Weight | 340.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(3,5-difluorophenyl)thiophen-2-yl)boronate (CAS 1402227-88-6)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(3,5-difluorophenyl)thiophen-2-yl)boronate (CAS 1402227-90-0)
- 3-Hydroxy-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-pyridyl]benzamide (CAS 2246909-59-9)
- 5-Hydroxy-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)nicotinamide (CAS 2246814-09-3)
- Phenyl 2-hydroxy-5-iodobenzoate (CAS 1131622-42-8)
- 5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1,4-diyl diacetate (CAS 87712-25-2)
- 1-((2-Hydroxy-1H-indol-3-yl)diazenyl)-2-(4-nitrophenoxy)ethan-1-one (CAS 81215-48-7)
- 1-(4-Hydroxy-3,5-dimethylphenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}-1-ethanone (CAS 344279-36-3)
Recommended Standards
- 3-[2-(4-bromophenyl)acetamido]thiophene-2-carboxylic acid (CAS 1016828-19-5)
- Ribavirin Impurity 43 (CAS 645-15-8)
- N-(4-(2,4-Dichlorophenyl)thiazol-2-yl)isoxazole-5-carboxamide (CAS 941993-87-9)
- 2-(2,6-Difluoro-4-(trifluoromethyl)phenoxy)-1,3-difluoro-5-methoxybenzene (CAS 2244084-30-6)
- (E)-1,2-Bis(4-(benzo[d]oxazol-2-yl)phenyl)ethene (CAS 36422-63-6)
- N1,N1-dimethyl-N4-(pyridin-4-ylmethyl)benzene-1,4-diamine (CAS 52725-19-6)
- 1-Methyl-5-(methylthio)-3-(5-nitrofuran-2-yl)-1H-1,2,4-triazole (CAS 61323-54-4)
- 4-Chloro-6-(4-(3-(4-methoxyphenyl)-1H-pyrazol-5-yl)piperidin-1-yl)pyrimidin-2-amine (CAS 1026093-00-4)
- N-(5-bromo-2-methoxyphenyl)propionamide (CAS 7044-79-3)
- n-(2-((2-Chloro-5-(n-(4-chlorophenyl)sulfamoyl)phenyl)amino)-2-oxoethyl)-5-methylthiophene-2-carboxamide (CAS 854358-28-4)
- 2-Aminohept-6-enoic acid (CAS 10325-17-4)
- Articaine Impurity 25 (CAS CATO-C4X-191225)
- 4-Chloro-5-methyl-2-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 68143-24-8)
- Semaglutide Impurity 6 (CAS 62-57-7)
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